Variations in the superficial venous system are very common, and the establishment of these variations at the preoperative period is important for determining the appropriate treatment modality. By presenting a case of rarely seen long-segment great saphenous vein (GSV) aplasia, we want to bring attention to the anatomical localization of GSV on routine color Doppler ultrasound imaging and GSV aplasia. (JAREM 2016; 6: 62-4)