ABSTRACT
Primary localized amyloidosis of the urinary bladder is a very rare disease with only 200 cases reported in the literature. However, it is an important condition because it can be easily confused with malignancy. It is most frequently observed during the fifth and sixth decade of life without sex preponderance. The classical presenting symptoms include painless gross hematuria and irritative lower urinary tract symptoms. The treatment of choice is transurethral resection, and histopathological evaluation is essential for the diagnosis and exclusion of malignancy. A close follow-up of the patient is required because of frequent recurrences. We present a case of primary localized amyloidosis of the urinary bladder with radiologic findings of a patient presenting with painless gross hematuria and mild dysuria.