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The Rate of Spondylodiscitis in Patients with Lomber Discectomy Using Single Dose Prophylactic Antibiotics
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Original Investigation
VOLUME: 9 ISSUE: 1
P: 1-6
December 2019

The Rate of Spondylodiscitis in Patients with Lomber Discectomy Using Single Dose Prophylactic Antibiotics

DOI: 10.5152/jarem.2018.2333
Furkan Diren 1
Mehmet Bülent Önal 2
Halil Can 3
Atilla Kırcelli 4
1. Department of Brain and Nerve Surgery, University of Health Sciences Gaziosmanpaşa Taksim Training and Research Hospital, İstanbul, Turkey
2. Acıbadem Mehmet Ali Aydınlar University Health Occupation High-School, İstanbul, Turkey
3. Clinic of Brain and Nerve Surgery, Biruni University Medicine Hospital, İstanbul, Turkey
4. Clinic of Brain and Nerve Surgery, Başkent University İstanbul Research Hospital, İstanbul, Turkey
No information available.
No information available
Received Date: 24.07.2018
Accepted Date: 24.07.2018
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ABSTRACT

Objective:

The incidence of spondylodiscitis following lumbar discectomy has been reported to range between 0.1% and 18.8% by various authors. The most common pathogen is Staphylococcus aureus.

Methods:

We collected retrospectively the medical records of 1154 patients who had the single-level or two-level disc herniation and were operated for lumbar microdiscectomy between 2007 and 2015 in our hospital. Of them, 554 were female and 600 were male. A total of 1062 patients underwent single-level, 91-level two-level lumbar microdiscectomy. All of these patients were given prophylactic single-dose cefazoline sodium during anesthesia in accordance with the recommendations of the surgical antimicrobial prophylaxis guidelines. Spondylodiscitis developed in 12 patients (1.03%). The comorbidities in patients treated for spondylodiscitis, isolated pathogens, antibiotic susceptibility, antibiotics used, and hospital stay were recorded.

Results:

Of the 12 patients, 7 were female and 5 were male. The mean age was 45.75±14.16 years. Eleven patients underwent single-level, and 1 two-level lumbar microdiscectomy procedures. 5 patients underwent discectomy from L4-5 and 8 patients from L5-S1 levels. Staphylococcus aureus was present in 3 patients (25%), Staphylococcus epidermidis in 4 (33%), Escherichia coli in 3 (25%), and 2 patients had no detected pathogens. The mean duration of hospital stay was 29.45±3.98 days, and in patients without spondylodiscitis, it was 1.99±0.81 days, meaning that there was a significant difference between these groups (p=0.0001).

Conclusion:

Although most surgeons tend to maintain antibiotic prophylaxis postoperatively or during the hospitalization period, our study found that a single dose prophylactic antibiotic administered during anesthesia induction did not increase the rate of spondylodiscitis, compared to the results found in the medical literature.